really hard to be profitable at these games if they are all you are playing. Low chip stacks and quick blinds lead to shove fests a lot of the time. That being said, if you can hit one of the big mulitipliers it can certainly pay off! The odds of hitting the big multipliers are incredibly rare though, and the variance will kill you in the long run unless you really know what you are doing. Best to stick to the small 9 man SNGs if you want to consistently be profitable!
good luck to you!