I have had good luck with killing one of the processes that run with Juicy and Lock. Although I have never seemed to have the problems with lock that I have with Juicy. All you need to do is run task manager, ctrl-alt-del, then click on task manager. Once there click on the Processes tab. If Juicy is already up and running find the process juicynotifier.exe, then highlight it and click on End Process button at the bottom. It will come up with a scary message that says ending processes will cause global warming or something like that. Just make sure that it is JuicyNotifier.exe that you are ending. You should see immediate improvement in performance.

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